To get to Puerto Guadal, you can take a flight from Santiago to Balmaceda and then continue by land transport along the Carretera Austral.
Another option is to take a flight to Coyhaique and from there continue by private vehicle or public transportation.
It can also be reached in your own vehicle from Coyhaique or from the south of Chile, through the Carretera Austral.
It is important to note that the route may be in poor condition due to the weather and topography of the area.
See more about how to get to Puerto Guadal