Santa Cruz is a city located in the O'Higgins Region, in central Chile.
It is located about 160 km south of Santiago and is located in the central valley of Chile, surrounded by mountains and vineyards.
The city is located on the banks of the Tinguiririca River, which is an important tributary of the Rapel River.
The area is known for its wine production and for its rich cultural and archaeological history, with several important sites of the Mapuche culture and of the ancient pre-Columbian inhabitants.
